So… although not yet sliced bread, there is a lot of development in easing things:
Smashing just release a nice wrap-up about the general aspects you’ll need to consider. Take it as a roadmap and consider it on your planning. Nowadays I ask the question -if not offer it all along- about wether the site will be iPhone or iPad ready.
If you happen to use a framework like Joomla, there are developments like T3 that provide a lot of things already done for you, and you just have to concentrate on your particular styling, if at all. See for example.
Surely there are many other great tools, frameworks and approaches. Like for example what Opera does with its mini-browser: a proxy that “mobilizes” the website…. why isn’t Google into this??? Right from the search results as they do know from where you are browsing.
Anyway, good luck with your endeavors, we’ll all need it!

